Long before Western science began studying psilocybin, Indigenous peoples across Mexico and South America worked with these mushrooms in sacred ceremony. Among the Mazatec, Mixtec, and other cultures, psilocybin was revered as a bridge to the spirit world — a way of receiving guidance, restoring harmony, and remembering one’s place in the web of life.
Unlike recreational use, ancestral ceremony placed psilocybin within ritual, song, prayer, and community. This sacred container is what transforms the mushroom from a simple compound into a spiritual teacher.